Journal: Cell

Article Title: Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning

doi: 10.1016/j.cell.2020.11.040

Figure Lengend Snippet: KEY RESOURCES TABLE

Article Snippet: Neuro. https://sccn.ucsd.edu/eeglab/index.php RRID: SCR_007292 SleepSign 3.0 Kissei Comtec http://www.sleepsign.com Ethovision 14 Noldus https://www.noldus.com/ethovision-xt/new Video Freeze Software Med Associates https://www.med-associates.com/product/video-fear-conditioning/ ScanImage (SI 2016b) Vidrio Technologies http://scanimage.vidriotechnologies.com/display/SIH/ScanImage+Home OMEGA OpenEye Scientific https://www.eyesopen.com/ CCP4 Collaborative Computational Project No. 4 https://www.ccp4.ac.uk Living Image PerkinElmer https://www.perkinelmer.com/product/li-software-for-spectrum-1-seat-add-on-128113 OmniPlex System Plexon https://plexon.com/products/omniplex-d-neural-data-acquisition-system-1/ ABET II Lafayette Instruments https://lafayetteneuroscience.com/products/abetii-operant-ctrl-software pCLAMP10 Molecular Devices https://mdc.custhelp.com/app/answers/detail/a_id/18779/~/axon%E2%84%A2pclamp%E2%84%A2-10-electrophysiology-data-acquisition-%26-analysis-software-download AxoGraph X N/A https://axograph.com/ Other Mantis Formulatrix N/A Fluorescent Platereader Tecan Infinite M200Pro IVIS Lumina Xenogen N/A Nanodrop Thermo 2000 Small animal Stereotax David Kopf Instruments In vivo fiber photometry experiments 1900 2-photon microscope Scientifica N/A Ti:Sapphire laser Coherent Chameleon ultra Axopatch-200B amplifier Molecular Devices 200B Vibrating Microtome Leica 1200 Mosquito TTP Labtech HTS Open in a separate window KEY RESOURCES TABLE Developed a machine learning approach for rapid binding-pocket redesign.

Techniques: Virus, Plasmid Preparation, Recombinant, Purification, Crystallization Assay, Concentration Assay, Sequencing, Software, In Vivo, Microscopy